Alex E Clark Selected Research

Neutralizing Antibodies

4/2023	Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.
1/2021	Zika virus is transmitted in neural progenitor cells via cell-to-cell spread and infection is inhibited by the autophagy inducer trehalose.

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Alex E Clark Research Topics

Disease

17	Infections 05/2024 - 01/2015
17	COVID-19 05/2024 - 10/2020
4	Zika Virus Infection 12/2022 - 10/2018
2	Virus Diseases (Viral Diseases) 05/2024 - 01/2018
2	Severe Acute Respiratory Syndrome 01/2023 - 11/2021
2	Neoplasms (Cancer) 01/2023 - 01/2023
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2023
1	Neglected Diseases 12/2022
1	COVID-19 rebound 05/2022
1	Reinfection 01/2022
1	Glioblastoma (Glioblastoma Multiforme) 01/2022
1	Brain Neoplasms (Brain Tumor) 01/2020
1	Congenital Abnormalities (Deformity) 01/2018
1	Cytomegalovirus Infections (Inclusion Disease) 01/2016

Drug/Important Bio-Agent (IBA)

9	Antiviral Agents (Antivirals)IBA 05/2024 - 01/2018
7	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2015
4	Interferon Type IIBA 05/2024 - 01/2021
4	AntibodiesIBA 01/2023 - 10/2020
3	InterferonsIBA 05/2024 - 01/2020
3	nirmatrelvir and ritonavir drug combinationIBA 04/2023 - 05/2022
3	remdesivirIBA 01/2023 - 01/2021
3	VaccinesIBA 01/2022 - 01/2021
3	TrehaloseIBA 01/2021 - 01/2016
2	N-methyl-valyl-amiclenomycin (BA 2)IBA 04/2023 - 01/2023
2	Neutralizing AntibodiesIBA 04/2023 - 01/2021
2	Messenger RNA (mRNA)IBA 01/2023 - 01/2021
2	Serine Proteases (Serine Protease)IBA 01/2023 - 01/2023
2	RNA (Ribonucleic Acid)IBA 01/2023 - 03/2022
2	Angiotensin-Converting Enzyme 2IBA 01/2023 - 01/2021
2	molnupiravirIBA 06/2021 - 01/2021
2	nirmatrelvirIBA 06/2021 - 01/2021
2	Cysteine Proteinase InhibitorsIBA 01/2021 - 10/2020
2	Immunoglobulin G (IgG)IBA 01/2021 - 10/2020
1	dolichyl-diphosphooligosaccharide - protein glycotransferase (oligosaccharyltransferase)IBA 05/2024
1	SARS-CoV-2 spike proteinIBA 05/2024
1	Adenine FDA LinkGeneric 01/2023
1	Coronavirus ReceptorsIBA 01/2023
1	IgA receptor (protein B)IBA 01/2023
1	ChemokinesIBA 01/2023
1	Surface-Active Agents (Surfactants)IBA 01/2023
1	CytokinesIBA 01/2023
1	Polysaccharides (Glycans)IBA 01/2023
1	EstersIBA 01/2023
1	EthersIBA 01/2023
1	Glycerol (Glycerine)FDA LinkGeneric 01/2023
1	Glycoproteins (Glycoprotein)IBA 01/2023
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2023
1	Peptide Hydrolases (Proteases)FDA Link 01/2023
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2023
1	ProdrugsIBA 01/2023
1	Protease Inhibitors (Protease Inhibitor)IBA 01/2023
1	Sterol Regulatory Element Binding ProteinsIBA 12/2022
1	LipidsIBA 12/2022
1	Transcription Factors (Transcription Factor)IBA 12/2022
1	Viral ProteinsIBA 03/2022
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 11/2021
1	Proline (L-Proline)FDA Link 03/2021
1	prolyl T RNA synthetaseIBA 03/2021
1	halofuginoneIBA 03/2021
1	DisaccharidesIBA 01/2021
1	IntegrinsIBA 01/2020
1	Phosphotransferases (Kinase)IBA 01/2016
1	Complement System Proteins (Complement)IBA 01/2015

Therapy/Procedure

6	Therapeutics 01/2022 - 01/2018
1	Drug Therapy (Chemotherapy) 01/2022